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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HBS1L
All Species:
26.67
Human Site:
T422
Identified Species:
53.33
UniProt:
Q9Y450
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y450
NP_001138630.1
684
75473
T422
Q
E
R
F
Q
E
I
T
G
K
L
G
H
F
L
Chimpanzee
Pan troglodytes
XP_001170393
684
75454
T422
Q
E
R
F
Q
E
I
T
G
K
L
G
H
F
L
Rhesus Macaque
Macaca mulatta
XP_001099850
683
75608
T422
Q
E
R
F
Q
E
I
T
G
K
L
G
H
F
L
Dog
Lupus familis
XP_533416
685
75774
T423
Q
E
R
F
Q
E
I
T
G
K
L
G
H
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZS7
682
75082
T420
Q
E
R
F
Q
E
I
T
G
K
L
G
H
F
L
Rat
Rattus norvegicus
Q6AXM7
679
74756
T417
Q
E
R
F
Q
E
I
T
G
K
L
G
H
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511405
675
74590
A412
E
E
R
F
Q
E
I
A
S
K
L
G
H
F
L
Chicken
Gallus gallus
XP_001234091
812
88631
T550
Q
E
R
F
Q
E
I
T
S
K
L
G
Q
F
L
Frog
Xenopus laevis
NP_001085851
678
75254
I416
Q
E
R
F
N
E
V
I
S
K
L
R
H
F
L
Zebra Danio
Brachydanio rerio
NP_955970
653
71635
V396
L
L
V
R
S
L
G
V
T
Q
L
A
V
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_652729
670
74146
V409
Q
D
R
F
T
E
I
V
T
K
L
K
S
F
L
Honey Bee
Apis mellifera
XP_623664
869
97147
E608
W
S
K
E
R
F
D
E
I
V
S
K
I
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.6
91.8
N.A.
89
88.7
N.A.
84
69.4
75.1
69.3
N.A.
46.9
40.5
N.A.
N.A.
Protein Similarity:
100
99.8
98.6
95.3
N.A.
93.5
93.1
N.A.
90.6
75.8
84.3
80.4
N.A.
65.1
58.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
86.6
66.6
6.6
N.A.
60
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
86.6
73.3
20
N.A.
66.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
9
75
0
9
0
84
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
84
0
9
0
0
0
0
0
0
0
84
0
% F
% Gly:
0
0
0
0
0
0
9
0
50
0
0
67
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% H
% Ile:
0
0
0
0
0
0
75
9
9
0
0
0
9
0
9
% I
% Lys:
0
0
9
0
0
0
0
0
0
84
0
17
0
0
0
% K
% Leu:
9
9
0
0
0
9
0
0
0
0
92
0
0
0
84
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
75
0
0
0
67
0
0
0
0
9
0
0
9
0
0
% Q
% Arg:
0
0
84
9
9
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
9
0
0
9
0
0
0
25
0
9
0
9
9
0
% S
% Thr:
0
0
0
0
9
0
0
59
17
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
9
17
0
9
0
0
9
0
9
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _